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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
20.91
Human Site:
S37
Identified Species:
35.38
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
S37
S
G
N
I
Q
R
I
S
Q
A
T
A
Q
I
K
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
S37
S
G
N
I
Q
R
I
S
Q
A
T
A
Q
I
K
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
S37
S
G
N
I
Q
R
I
S
Q
A
T
A
Q
I
K
Dog
Lupus familis
XP_535342
274
31382
S37
S
G
N
I
Q
R
I
S
Q
A
T
A
Q
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
S37
S
G
N
I
Q
R
I
S
Q
A
T
A
Q
I
K
Rat
Rattus norvegicus
O70257
261
29832
N37
A
E
I
Q
R
T
L
N
Q
L
G
T
P
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
D30
S
Q
L
G
T
K
Q
D
S
S
K
L
Q
E
N
Chicken
Gallus gallus
XP_001232002
272
30779
Y37
N
V
Q
R
I
A
Q
Y
T
A
Q
I
K
N
L
Frog
Xenopus laevis
NP_001079671
259
29246
G39
R
I
V
V
H
Q
L
G
T
A
Q
D
T
A
E
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
G37
Q
K
I
T
Q
N
T
G
Q
I
K
S
M
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Q51
R
G
M
I
D
K
V
Q
D
N
V
E
E
V
K
Honey Bee
Apis mellifera
XP_396269
271
30684
V37
I
L
K
I
S
Q
N
V
S
S
M
Q
K
M
V
Nematode Worm
Caenorhab. elegans
O16000
291
33234
A50
R
G
S
V
D
I
I
A
N
N
V
E
E
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
S44
A
A
G
I
F
R
I
S
T
A
V
N
S
F
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
13.3
6.6
6.6
13.3
N.A.
20
6.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
26.6
20
33.3
26.6
N.A.
46.6
33.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
8
0
8
0
58
0
36
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
8
8
0
0
8
0
0
8
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
15
15
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
15
% F
% Gly:
0
50
8
8
0
0
0
15
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
15
58
8
8
50
0
0
8
0
8
0
36
0
% I
% Lys:
0
8
8
0
0
15
0
0
0
0
15
0
15
0
50
% K
% Leu:
0
8
8
0
0
0
15
0
0
8
0
8
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
8
8
0
% M
% Asn:
8
0
36
0
0
8
8
8
8
15
0
8
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
8
8
8
43
15
15
8
50
0
15
8
43
8
0
% Q
% Arg:
22
0
0
8
8
43
0
0
0
0
0
0
0
0
0
% R
% Ser:
43
0
8
0
8
0
0
43
15
15
0
8
8
0
0
% S
% Thr:
0
0
0
8
8
8
8
0
22
0
36
8
8
0
0
% T
% Val:
0
8
8
15
0
0
8
8
0
0
22
0
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _